Allele/Variant

Tg(UAS-Smo*W539L)1Amc

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

UAS-Smo*

Description

This transgene contains five upstream activating sequence (UAS) elements, a Wnt1 promoter, the rat Smo cDNA containing a W539L mutation, the human placental alkaline phosphatase cDNA under the control of an internal ribosomal entry site, lacZ, and a poly A signal from the murine Wnt1 gene. UAS elements drive the expression of the mutated ligand-independent activated rat Smo gene. Expression of this transgene is dependent on GAL4 expression.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

Smo (Rno)

Knock-down Targets

None

Regulatory Regions

None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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