Cd19^tm1(cre)Thr

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Species

Mus musculus

Symbol

Cd19^tm1(cre)Thr

Category

allele

Allele of gene

Cd19

Transgenic Constructs

Synonyms

• CD19-cre

Description

In frame insertion of a cre recombinase gene into the first coding exon followed by an frt-flanked neomycin cassette. A frameshift mutation was also introduced into exon 5. This allele expresses cre recombinase specifically in B lineage cells throughout development. This allele was made using the same construct used for Cd19^tm1(cre)Cgn, however CCB ES cells were used for targeting.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations