Version: 8.0.0
Date: Tue Jan 28 2025
Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell
MGI:3590083Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell

Species
Mus musculus
Symbol
Tg(CD4,HLA-DQA1,HLA-DQB1)N8Ell
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • DQ6 transgene
  • HLA-DQ6 transgene
Description
The human CD4 gene lacking one exon but including its promoter was fused downstream of a mouse CD4 enhancer element then mixed with a large DNA fragment containing both HLA-DQA*0102 and HLA-DQB*0602 and injected into NOD/LtJ one celled embryos. A single founder line is maintained.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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