Allele/Variant

Fgfr2tm2Cxd

Species
Mus musculus
Symbol
Fgfr2tm2Cxd
Category
allele
Allele of gene
Fgfr2
Transgenic Constructs
None
Synonyms
  • Fgfr2Neo-S252W
  • Fgfr2neo250
Description
A targeting vector containing a GG substitution resulted in a Ser250Trp mutation in exon 7. A floxed neo was inserted upstream of exon 7. This allele was a hypomorph, expressed only in significantly reduced levels. Removal of the floxed neo restores expression levels.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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