Srf^tm1Rjs

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Species

Mus musculus

Symbol

Srf^tm1Rjs

Category

allele

Allele of gene

Srf

Transgenic Constructs

None

Synonyms

• SRF^-
• SRF^LacZ

Description

Sequence encoding the DNA binding and dimerization domains of the protein was replaced by the insertion of an NLS-betagalactosidase-neomycin cassette. In situ hybridization demonstrated expression in embryos ranging from E7.5 to E9.5 predominantly in the cardiac crescent and later in the heart tube, the somites, and the precondensed mesenchyme in the tail, consistent with the expression of the endogenous gene.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations