Allele/Variant

Tg(Prnp-MAPT)4Hlmc

Species
Mus musculus
Symbol
Tg(Prnp-MAPT)4Hlmc
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • JN4
Description
The mouse prion protein promoter was used to drive expression of human microtubule-associated protein tau cDNA with exon 10, but lacking exons 2 and 3. These exons encode four-repeat tau without amino-terminal inserts. Mutant mice expressed the transgene at a level below that of endogenous tau.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations