Uchl1^tm1Dgen

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Species

Mus musculus

Symbol

Uchl1^tm1Dgen

Category

allele

Allele of gene

Uchl1

Transgenic Constructs

None

Synonyms

None

Description

Exons 6 through 8 and the first 6 bases of exon 9 were replaced by a lacZ-neomycin cassette. RT-PCR analysis detected a gene transcript in most tissues analyzed except for Harderian glands, liver, lymph nodes, bone marrow and skeletal muscle. Beta-galactosidase expression from this allele was detectable in brain, spinal cord, eyes, heart, pancreas, kidney, urinary bladder, pituitary gland, adrenal glands, testis, prostate gland, ovary and cervix. Western blot analysis of brain and spinal cord homogenates failed to detect any protein product.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations