Gabra3^tm1Dgen

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Species

Mus musculus

Symbol

Gabra3^tm1Dgen

Category

allele

Allele of gene

Gabra3

Transgenic Constructs

None

Synonyms

None

Description

A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the brainstem and olfactory bulb and lower levels in all other tissues analyzed. Beta-galactosidase expression from this allele is detectable in brain, dorsal horns and dorsal root ganglia of the spinal cord and lens of the eye. Expression was also detectable in aorta, a few cells of the heart and kidney, some blood vessels of the lung and liver and tunica albuginea of testis.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations