Version: 8.0.0
Date: Tue Jan 28 2025
Smarca4tm1.2Pcn
MGI:3605892
Allele of Smarca4
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Smarca4tm1.2Pcn

Species
Mus musculus
Symbol
Smarca4tm1.2Pcn
Category
allele
Allele of gene
Smarca4
Transgenic Constructs
None
Synonyms
  • Brg1F
  • brg1FL
Description
A single loxP site was inserted upstream of exon 18 and a floxed hygromycin resistance cassette was inserted downstream of exon 19. The hygromycin resistance cassette was selectively excised from correctly targeted ES cells by transient transfection with a cre-expression vector. Exons 18 and 19, encoding part of the ATPase-helicase motifs, were thus flanked by loxP sites in the resulting ES cells.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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