Allele/Variant

Psen1tm1Dgf

Species
Mus musculus
Symbol
Psen1tm1Dgf
Category
allele
Allele of gene
Psen1
Transgenic Constructs
None
Synonyms
  • PS-1P264L
  • PS1P264L
Description
A targeting construct was designed to insert a P264L mutation into exon 8. Northern blot demonstrated mRNA levels were comparable in mutants and wild-type mice. Western blot indicated that despite normal mRNA expression, expression of N- and C-terminal fragments was reduced by about 50%.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
No records match query. Try removing filters.
Showing 0 - 0 of 0 rows
per page

    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
    No records match query. Try removing filters.
    Showing 0 - 0 of 0 rows
    per page