Smarca4^enu1

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Species

Mus musculus

Symbol

Smarca4^enu1

Category

allele

Allele of gene

Smarca4

Transgenic Constructs

None

Synonyms

• Brg1^enu1
• Smarca4^m1Mag

Description

Males carrying the curly whisker allele were mutagenized with ENU to result in this hypomorphic allele. An A to G transition in exon 23 caused an E1083G substitution in a highly conserved region of the catalytic ATPase domain. The mutation did not affect mRNA or protein stability based on Orthern blot and Wesetern blot analyses, respectively.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations