Allele/Variant

Abcd2tm1Apuj

Species
Mus musculus
Symbol
Abcd2tm1Apuj
Category
allele
Allele of gene
Abcd2
Transgenic Constructs
None
Synonyms
  • abcd2 KO
  • Abcd2-
Description
Exons 4 through 6 were deleted. Western blot showed a complete lack of protein in all tissues of mutant mice. Quantitative RT-PCR confirmed absence of full-length transcript, although shorter, smir-type and low expressed fragments were detected, consistent with nonsense-mediated mRNA decay process.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations