Version: 8.0.0
Date: Tue Jan 28 2025
Pcsk5tm1.1Prat
MGI:3612544
Allele of Pcsk5
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Pcsk5tm1.1Prat

Species
Mus musculus
Symbol
Pcsk5tm1.1Prat
Category
allele
Allele of gene
Pcsk5
Transgenic Constructs
None
Synonyms
  • Pcsk5delta4
Description
Cre-mediated excision removed exon 4, an exon encoding one of the three catalytic residues, the Asp173 that is essiential for enzyme activity. QPCR and sequencing confirmed that exons 3 and 5 were fused in the mutant allele. A truncated form of the protein was produced from the allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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