Version: 8.0.0
Date: Tue Jan 28 2025
Ireb2tm1.2Mwh
MGI:3613524
Allele of Ireb2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ireb2tm1.2Mwh

Species
Mus musculus
Symbol
Ireb2tm1.2Mwh
Category
allele
Allele of gene
Ireb2
Transgenic Constructs
None
Synonyms
  • Irp2delta
Description
Exon 3 was removed from Ireb2tm1.1Mwh by mating with mice expressing Tg(Pgk1-cre)1Lni, creating a null allele. Removal of exon 3 creates a frameshift with premature termination of translation in exon 4. Western blotting confirmed absence of protein in kidney, duodenum, liver and spleen extracts.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
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