Ikbkg^tm1Mka

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Species

Mus musculus

Symbol

Ikbkg^tm1Mka

Category

allele

Allele of gene

Ikbkg

Transgenic Constructs

None

Synonyms

• Ikkgamma^-
• NEMO^-

Description

This allele was created by using one of two vectors. The first vector was designed to insert a beta-lactamase cassette, a stop codon and a neomycin resistance gene in frame with the first ten codons. The second vector was designed to remove most of the coding sequence in the first exon and replace it with a beta-lactamase and neomycin resistance cassette. Western blot failed to detect protein in mutant ES cells.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations