Allele/Variant

Tg(Tagln-rtTA-cre)1Llw

Species

Mus musculus

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

SM22alphartTACre

Description

The transgelin promoter drives the expression of the rtTA transactivator in this transgene. When doxycycline is present, the transactivator binds to the tet responsive element (tetO) to direct cre expression. The reverse tetracycline-controlled transactivator was modified to be inducible by lower concentrations of doxycycline with greater control of basal expression.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

Tagln

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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