Version: 8.0.0
Date: Tue Jan 28 2025
Gria2tm2Rlh
MGI:3623451
Allele of Gria2
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Gria2tm2Rlh

Species
Mus musculus
Symbol
Gria2tm2Rlh
Category
allele
Allele of gene
Gria2
Transgenic Constructs
None
Synonyms
  • GluR2 K882A
Description
A targeting vector was designed to insert a floxed neo into the locus as well as the K882A substitution into the exon encoding transmembrane domain 4 and the C terminus region. The neo was subsequently removed via cre recombinase expression. A reduction in the levels of the long isoform was found particularly in mutants of 1 month of age.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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