Allele/Variant

Tg(Afp-IGFBP1)16Csw

Species
Mus musculus
Symbol
Tg(Afp-IGFBP1)16Csw
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
A 9.2kb transgene containing the human IGFBP1 cDNA under the control of the mouse alpha-fetoprotein regulatory sequence was microinjected into the pronuclei of C57BL/6 x CBA F1 embryos. Four founder lines were established (2,3,4,16). Line 16 contains 8 copies of the transgene and expresses at high levels in fetal liver and yolk sac with lower levels of expression in gut epithelial cells and brain glial cells.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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    Disease Associations

    Association
    Disease Qualifier
    Disease
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