Hpn^tm1Qwu

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Species

Mus musculus

Symbol

Hpn^tm1Qwu

Category

allele

Allele of gene

Hpn

Transgenic Constructs

None

Synonyms

• Tmprss1^-

Description

Exons 5-8, which encode the conserved activation site and most of the catalytic domain, were deleted and replaced with a neomycin selection cassette. Northern blot analysis of total liver RNA derived from mutant mice demonstrated that no detectable transcript is expressed from this allele.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations