Version: 8.0.0
Date: Tue Jan 28 2025
Myd88lkd
MGI:3641234
Allele of Myd88
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Myd88lkd

Species
Mus musculus
Symbol
Myd88lkd
Category
allele
Allele of gene
Myd88
Transgenic Constructs
None
Synonyms
  • Lkd
  • Myd88m1Btlr
Description
This mutation, identified in a screen of G3 progeny of ENU treated mice for responses to various toll-like receptor ligands, is an A-to-G transition resulting in replacement of tyrosine with cysteine at amino acid 116 (Y116C), between the death domain (aa 19-109) and the toll-interleukin 1 receptor (TIR) domain (aa 160-296) of the protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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