Allele/Variant

Runx3tm2Yg

Species
Mus musculus
Symbol
Runx3tm2Yg
Category
allele
Allele of gene
Runx3
Transgenic Constructs
None
Synonyms
  • Runx3deltaV
  • Runx3VWRPY-
Description
A targeting vector was designed such that the codons of the five C-terminal amino acids, VWRPY, were changed to the stop codon UAG and to codons encoding substituted amino acids designed to create a new NotI site. A loxP-flanked neo was included in intron 5 and was subsequently removed via cre-mediated excision. RT-PCR and Western blot analyses demonstrated expression of the mutant transcript and protein, respectively.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations