Atp2b2^jog

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Species

Mus musculus

Symbol

Atp2b2^jog

Category

allele

Allele of gene

Atp2b2

Transgenic Constructs

None

Synonyms

None

Description

An intracisternal A particle (IAP) was found to have inserted at the downstream donor splice site of exon 1. Primary transcripts are prematurely terminated and a chimeric mRNA including fused IAP sequence is produced. Expression of full length mRNA is reduced to about 5% of normal. Expression of full length and chimeric mRNA is reduced to about 60% relative to controls.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations