Allele/Variant

Klhl1/Atxn8ostm1Mdk

Species
Mus musculus
Symbol
Klhl1/Atxn8ostm1Mdk
Category
allele
Allele of gene
Klhl1
Transgenic Constructs
None
Synonyms
  • Klhl1/Klhl1astm1Mdk
  • Klhl1flox
Description
A loxP site was inserted into the transcription start site of Klhl1, which is also the upstream region of the polyA signal of Klhl1as. A neo cassette flanked with 2 FRT sites and a 3' loxP site were inserted into the first intron of Klhl1, which is downstream of the transcription start site of Klhl1as. Crossing with mice that express FLP in the germline resulted in the removal of the neo, leaving exon 1 of Klhl1 flanked by loxP sites and the complete coding sequence for Klhl1as flanked by loxP sites.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
References
impaired coordinationMGI
thin cerebellar molecular layerMGI
Showing 1 - 2 of 2 rows
per page

Disease Associations