Allele/Variant

Ciitatm1.1Dim

Species
Mus musculus
Symbol
Ciitatm1.1Dim
Category
allele
Allele of gene
Ciita
Transgenic Constructs
None
Synonyms
  • CIITA0
Description
A single loxP site was introduced 5' to exon 2 and a loxP-flanked thymidine kinase-neomycin fusion gene was inserted 3' to exon 3. Cre-mediated deletion of the intervening sequences was accomplished by mating mutant mice to CMV-cre mice, deleting the DNA encoding the major transactivation domain. RT-PCR analysis on spleen and thymus RNA indicated that no detectable transcript is expressed from this allele.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations