Gabbr1^tm3Bet

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Species

Mus musculus

Symbol

Gabbr1^tm3Bet

Category

allele

Allele of gene

Gabbr1

Transgenic Constructs

None

Synonyms

• 1a^-
• GABAB(1a)^-

Show All 4

Description

The start codon for the B1a isoform of Gabbr1 was converted into a stop codon to prevent translation of the B1a isoform. A putative alternative start site was also mutated and a floxed neomycin cassette was inserted in the introns between exons 2a and 3a. The neomycin cassette was removed by crossing with mice expressing Cre-recombinase under the control of the cytomegalus virus promoter. Northern blot analysis confirmed absence of the B1a isoform.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations