Allele/Variant

Map2k6tm1Ina

Species
Mus musculus
Symbol
Map2k6tm1Ina
Category
allele
Allele of gene
Map2k6
Transgenic Constructs
None
Synonyms
  • MKK6-
Description
A neomycin resistance cassette was inserted into exon 3, in the region encoding the kinase domain of the protein. RT-PCR analysis detects no transcript from the disrupted gene in thymocyte RNA from homozygous mutant mice. Immunoblot analysis detects no protein product from the targeted gene in thymocyte lysates from homozygous mutant mice and a reduced amount in lysates from heterozygous mutants.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations