Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Cacna1atm2.1Maag
- Species
- Mus musculus
- Symbol
- Cacna1atm2.1Maag
- Category
- allele
- Allele of gene
- Cacna1a
- Transgenic Constructs
- None
- Synonyms
- Cacna1aflox
- Description
- This allele contains loxP sites flanking exon 4. A neo cassette has been removed via cre mediated recombination. Northern blot detected normal levels of RNA in these mutants.
- Additional Information
- Literature
Phenotypes
Phenotype | Annotation details | Source | References |
|---|---|---|---|
| abnormal brain interneuron morphology | MGI | ||
| abnormal cerebellar granule cell morphology | MGI | ||
| abnormal cerebellar molecular layer | MGI | ||
| abnormal cerebellum morphology | MGI | ||
| ataxia | MGI | ||
| impaired balance | MGI | ||
| impaired coordination | MGI | ||
| impaired righting response | MGI | ||
| no abnormal phenotype detected | MGI | ||
| Purkinje cell degeneration | MGI |