Allele/Variant

Surf1tm2.1Zev

Species
Mus musculus
Symbol
Surf1tm2.1Zev
Category
allele
Allele of gene
Surf1
Transgenic Constructs
None
Synonyms
  • Surf1loxP
Description
This allele results after the cre mediated excision of the neomycin resistance cassette in Surf1tm2Zev. The loxP remaining in exon 7 disrupts the reading frame from nucleotide 674 downstream of the cDNA and the replacement of the codon encoding N225 with a TAA stop codon. This frame shift would putatively result in the elimination of 81 amino acids from the carboxy terminus, however, no protein was detected by Western blot.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations