Version: 8.0.0
Date: Tue Jan 28 2025
Grin2btm1(GRIN2A/GRIN2B)Twr
MGI:3699608
Allele of Grin2b
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Grin2btm1(GRIN2A/GRIN2B)Twr

Species
Mus musculus
Symbol
Grin2btm1(GRIN2A/GRIN2B)Twr
Category
allele
Allele of gene
Grin2b
Transgenic Constructs
None
Synonyms
None
Description
A targeting vector was designed to insert the 6 kb long human chimeric cDNA clone GRIN2A/GRIN2B in-frame, leaving the 34 amino-acid long signal peptide sequence intact. Amino acid residues 35-282 of the human glutamate receptor, ionotropic, NMDA2A (epsilon 1) and the carboxyl terminal remainder of the human glutamate receptor, ionotropic, NMDA2B (epsilon 2) residues were inserted into the mouse locus. The vector was inserted into exon 4 (the first coding exon) of the endogenous locus.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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