Version: 8.0.0Date: Tue Jan 28 2025
Allele/Variant
Ndor1Tg(UBC-cre/ERT2)1Ejb
- Species
- Mus musculus
- Symbol
- Ndor1Tg(UBC-cre/ERT2)1Ejb
- Category
- allele
- Allele of gene
- Ndor1
- Transgenic Constructs
- Synonyms
- Cre-ER
- Cre-ERT2
- Description
- This Cre-ERT2 transgenic mouse line was generated via lentitransgenesis; a self-inactivating lentiviral vector was designed with the human ubiquitin C (UBC) promoter sequence upstream of a Cre-ERT2 fusion gene (Cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). Cre-ERT2-expressing lentivirus were microinjected into the perivitelline space of one-cell zygotes (129SvEv;C57BL/6 mixed genetic background). Mice display tamoxifen-inducible Cre activity in all tissue types. Line 1 inserted into the gene at 25249816-25249821 (Build GRCm38/mm10) resulting in a 5 bp deletion.
- Additional Information
- Literature
Transgenic Constructs
This allele contains 1 transgenic construct- Symbol
- Expressed Components
- None
- Knock-down Targets
- None
- Regulatory Regions