Allele/Variant

Tg(Tcra,Tcrb)24Efro

Species

Mus musculus

Symbol

Tg(Tcra,Tcrb)24Efro

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

qCII24

Description

Transgenic constructs containing the mouse alpha and beta chain of the T cell receptor recognizing both bovine and mouse type II collagen (260-267) were cloned from the Tcra-V11.1,Tcra-J(J17) and Tcrb-V8.3,Tcrb-D(D1),Tcrb-J(J1.4) expressing I-Aq-restricted T cell hybridoma qCII85.33. Line 24 was established. The transgenic T cell receptor is expressed on >90% of CD4+ T cells in the spleen and lymph nodes. >90% of alphabeta+ T cells in the thymus.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol
Expressed Components: None
Knock-down Targets: None
Regulatory Regions: None

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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