Allele/Variant

Tg(Npy-hrGFP)1Lowl

Species
Mus musculus
Symbol
Tg(Npy-hrGFP)1Lowl
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
  • NPY-GFP
  • Npy-hrGFP
Description
A bacterial artificial chromosome (BAC) was modified by inserting a humanized Renilla GFP (hrGFP, Stratagene) sequence into the translational start site of the mouse neuropeptide Y (Npy) gene. Correctly transformed and targeted bacteria were used to isolate the ~200 kb transgenic construct (called "NPY-GFP"). This NPY-GFP transgene was used for pronuclear injection into fertilized one-cell stage FVB embryos. Founder line 1 showing germline transmission was established. Brain tissues show GFP fluorescence when exposed to UV light.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

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    Disease Associations

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