Version: 8.0.0
Date: Tue Jan 28 2025
Tg(Nppa-cre)4Vmc
MGI:3710255Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Tg(Nppa-cre)4Vmc

Species
Mus musculus
Symbol
Tg(Nppa-cre)4Vmc
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Nppa-cre4
Description
The transgenic construct consisted of a sequence fragment encoding cre recombinase, a nuclear localization signal, and a consensus Kozak signal inserted at the start codon of the mouse genomic Nppa sequence. The 0.7 kbp Nppa proximal promoter region (-3kbp to +4 kbp relative to the transcription start site) was included. The mouse Nppa proximal promoter drives expression of cre recombinase in atrial cardiomyocytes beginning around E10.5. Complete expression is observed around E14.5. Some expression was observed in the inflow tract.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
None
Knock-down Targets
None
Regulatory Regions
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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