Allele/Variant

Ncf4tm2Pth

Species
Mus musculus
Symbol
Ncf4tm2Pth
Category
allele
Allele of gene
Ncf4
Transgenic Constructs
None
Synonyms
  • P40phox-
Description
A translational stop codon was introduced at codon 73 in exon 3 in the targeting vector. The vector also contains both a tACE-Cre and neoR module. Recombination in ES cells introduced the stop codon into the Ncf4 sequence. When chimeras were bred, tACE promoter activity in testes promoted Cre/loxP-mediated deletion of the cassette, leaving 59 bp of foreign DNA. No Ncf4 protein can be detected by antibodies in homozygous mice.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations