Allele/Variant

Tg(Fabp4-Plin*)1Asg

Species
Mus musculus
Symbol
Tg(Fabp4-Plin*)1Asg
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • Peri Adelta1-6
Description
A mouse Plin cDNA that had serine-to-alanine mutations made in all 6 protein kinase A phosphorylation sites using recombinant adenoviruses (Muta-Gene Phagemid in vitro mutagenesis kit (Bio-Rad)). The cDNA was FLAG-tagged at the carboxy terminus via PCR and was placed in a pBluescript vector containing the Fabp2 enhancer/promoter region, the SV40 small tumor antigen splice site, and polyadenylation signal sequence. This construct was injected in C57BL/6 fertilized oocytes. Mice express the transgene almost exclusively in brown adipose tissue.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations