Version: 8.0.0
Date: Tue Jan 28 2025
Ewsr1tm1Sblee
MGI:3713772
Allele of Ewsr1
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Ewsr1tm1Sblee

Species
Mus musculus
Symbol
Ewsr1tm1Sblee
Category
allele
Allele of gene
Ewsr1
Transgenic Constructs
Synonyms
  • EWS-WT1(+KTS)
  • Ews-
Description
A loxP-flanked transcriptional stop signal in antisense orientation was inserted into intron 6, exon 7 was fused to human WT1 (lysine, threonine, and serine version termed +KTS) with a C-terminal FLAG tag, and a 3' neo cassette, replacing exons 8 through 11, was inserted by homologous recombination. The absence of endogenous protein product was confirmed by western blot analysis.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
    References
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