Allele/Variant

Tg(AMELX-LRAP)9Gibs

Species
Mus musculus
Symbol
Tg(AMELX-LRAP)9Gibs
Category
allele
Allele of gene
None
Transgenic Constructs
None
Synonyms
None
Description
5.5 kb of upstream bovine AMELX gene sequence plus untranslated exon 1 and intron 1 was fused to a bovine LRAP cDNA, and followed by a bovine polyadenylation signal sequence from the bovine AMELX gene. RT-PCR analysis demonstrated that this transgene is expressed in tooth germ by 15 days of fetal age, and western blot analysis demonstrated protein expression in molar tooth germs. Four lines of transgenice mice were produced; in addition to line 9, lines 15, 16 and 22 were made.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations