Ror2^{Tn(pb-ZG-s)1.1Mrc}

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Species

Mus musculus

Symbol

Ror2^{Tn(pb-ZG-s)1.1Mrc}

Category

allele

Allele of gene

Ror2

Transgenic Constructs

None

Synonyms

None

Description

piggyBac transposase mediated recombination inserted the ZG-s transposable gene-trap vector into intron 2. The gene-trap vector consists of piggyBac terminal repeats and internal sequence with all potential splice donor sites removed flanking a loxP site, a splice acceptor site, an IRES-beta-galactosidase-polyA cassette, an FRT site, a CAG-eGFP-polyA cassette, a loxP site, a lox5171 site, and an FRT site. Flp-mediated recombination removes the eGFP cassette. Cre-mediated recombination removes the splice acceptor and beta-galactosidase cassette restoring gene expression.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations