Allele/Variant

Cyp17a1tm1Vpap

Species
Mus musculus
Symbol
Cyp17a1tm1Vpap
Category
allele
Allele of gene
Cyp17a1
Transgenic Constructs
None
Synonyms
None
Description
A neo cassette replaced the entire gene as well as 3.3 kb sequence upstream and 3.5 kb sequence downstream of the gene. RT-PCR analysis determined that expression of adjacent genes was not affected. Analysis of 129 derived sperm from chimeras showed reduced mRNA and protein expression, as determined by quantitative PCR and western analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
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