Allele/Variant

Trp53tm5Xu

Species
Mus musculus
Symbol
Trp53tm5Xu
Category
allele
Allele of gene
Trp53
Transgenic Constructs
None
Synonyms
  • p53R273H
Description
A loxP site flanked neomycin resistance gene cassette and a human gene fragment containing an amino acid substitution of histidine with arginine at position 273 (p.R273H) replaced intron 4 through 10. The neo cassette was removed by cre-mediated recombination. The presence of the mutations was confirmed by Southern blot and sequence analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations