Gria1^tm4Rlh

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Species

Mus musculus

Symbol

Gria1^tm4Rlh

Category

allele

Allele of gene

Gria1

Transgenic Constructs

None

Synonyms

None

Description

Serines 831, 839, 845 and threonines 838 and 840 were mutated to alanine by PCR mutagenesis prior to homologous recombination. A floxed neo cassette was inserted upstream of the last conding exon was removed by cre-mediated recombination following a cross to mice containing Tg(CMV-cre)1Nagy. Western blot analysis with was performed to confirm the presence of the protein but loss of the phosphorylation sites.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations