Version: 8.0.0
Date: Tue Jan 28 2025
Cblbtm1Wlan
MGI:3762926
Allele of Cblb
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Cblbtm1Wlan

Species
Mus musculus
Symbol
Cblbtm1Wlan
Category
allele
Allele of gene
Cblb
Transgenic Constructs
None
Synonyms
  • Cbl-b BR
  • Cbl-b(C373A)
Description
A targeting vector introduced a cysteine (TGC) to alanine (GCG) substitution at amino acid position 373 (C373A) encoded within exon 8. A loxP flanked pGKNeo cassette was removed by crossing mice with Cre-transgenic mice, leaving behind a single loxP site. Western analysis of bone marrow derived mast cells from homozygotes indicated protein expression was similar to wild-type protein.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
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