Version: 8.0.0
Date: Tue Jan 28 2025
Flt3tm1Dgg
MGI:3763385
Allele of Flt3
Mus musculus
SummaryTransgenic ConstructsGenomic Variant InformationVariant Molecular ConsequencesPhenotypesDisease Associations
Allele/Variant

Flt3tm1Dgg

Species
Mus musculus
Symbol
Flt3tm1Dgg
Category
allele
Allele of gene
Flt3
Transgenic Constructs
None
Synonyms
  • FLT3/ITD
  • Flt3ITD
Description
The human W51 mutation which causes the duplication of amino acid 595 to 601 (REYEYDL; AGAGAATATGAATATGATCTC) was inserted in-frame into exon 14, replacing the endogenous single copy (RDYEYDL; AGGGACTATGAATATGACCTT). A loxP site flanked neomycin selection cassette was inserted into intron 15.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

Phenotype
Annotation details
Source
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    Disease Associations

    Association
    Disease Qualifier
    Disease
    Annotation details
    Evidence
    Source
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