Allele/Variant

Egfrtm1Msi

Species
Mus musculus
Symbol
Egfrtm1Msi
Category
allele
Allele of gene
Egfr
Transgenic Constructs
None
Synonyms
  • EGFRf
Description
A targeting vector in which the promoter and the first exon of the gene are flanked by loxP sites was constructed. The upstream loxP site with a diagnostic XmaCI restriction site was placed into a BSMI site, and the downstream loxP site was cloned into the SexA1 site. A frt-flanked neomycin cassette was placed between exon 1 and the downstream loxP site. Recombination was confirmed through PCR and Southern blot analysis.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations