Allele/Variant

Tg(Alb-PLG)1Dgi

Species
Mus musculus
Symbol
Tg(Alb-PLG)1Dgi
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
None
Description
A cassette containing the human PLG cDNA from nucleotide -13 (A of ATG initiation codon as +1) to +2476 (including the entire coding sequence) was followed by the green fluorescent protein (EGFP) coding sequence, preceded by an internal ribosome entry site sequence (IRES) and a bacterial kanamycin-resistant gene (KAN). A chimeric intron with optimized splice signals from the pCI expression vector was placed upstream of the PLG cDNA. Homologous recombination between the transgene targeting construct and the murine Alb BAC was carried out in E. coli, replacing the murine Alb gene (from nucleotide -12 to exon 12) by the transgene cassette. EGFP expression is not detected.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations