Allele/Variant

Adamts13tm1Myta

Species
Mus musculus
Symbol
Adamts13tm1Myta
Category
allele
Allele of gene
Adamts13
Transgenic Constructs
None
Synonyms
  • Adamts13-
Description
The exons 3-6 that encode the catalytic domain of the protein were replaced with a neomycin resistance cassette. Elimination of gene expression in homozygotes was confirmed by quantitative RT PCR on liver RNA and by the lack of enzymatic activity of the gene product in plasma.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations