Allele/Variant

Tg(Pf4-icre)Q3Rsko

Species

Mus musculus

Symbol

Tg(Pf4-icre)Q3Rsko

Category

allele

Allele of gene

None

Transgenic Constructs

Synonyms

(Pf4)-Cre
Pf4-Cre

Description

A transgene was created from a BAC where cre-recombinase is driven by the Cxcl4 (Platelet factor 4) promoter. This transgene also contains the Cxcl3, Cxcl5, Ppbp, and Cxcl15 genes. This line has one copy of the transgene inserted with expression restricted to megakaryocytes and platelets, as demonstrated by RT-PCR and Western blotting.

Additional Information

Literature

Transgenic Constructs

This allele contains 1 transgenic construct

Symbol

Expressed Components

None

Knock-down Targets

None

Regulatory Regions

All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

No data available

Phenotypes

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Disease Associations

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