Ep400^tm1Fuku

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Species

Mus musculus

Symbol

Ep400^tm1Fuku

Category

allele

Allele of gene

Ep400

Transgenic Constructs

None

Synonyms

• mDom^deltaN

Description

Part of exon and intron 2 were replaced with a neo cassette. The absence of transcript was confirmed by whole mount in situ hybridization using E8.5 embryos. An aberrant transcript lacking the 471 N-terminal amino acids is produced from an initiation site in exon 3. The lack of the full-length protein product and presence of a shorter peptide lacking the N-terminus was confirmed by western blot analysis on embryonic fibroblasts derived from E8.5 embryos.

Additional Information

Literature

Transgenic Constructs

Genomic Variant Information

Variant Molecular Consequences

Phenotypes

Disease Associations