Allele/Variant

Tg(COL1A1)73Prc

Species
Mus musculus
Symbol
Tg(COL1A1)73Prc
Category
allele
Allele of gene
None
Transgenic Constructs
Synonyms
  • line V
Description
These mice express a mini-gene construct that contains the 5'- and 3'-ends of the human gene for the pro-alpha(1) collagen chain but lack a large central region containing 41 exons. The mini-gene includes 2.5 kilobases of the 5'-promoter region, the first 5 exons and introns, the last 6 exons and introns, and about 2 kilobases of the 3"flanking region. The junction between the 5'- and 3'-halves of the mini-gene was made in introns so as to preserve the consensus sequences for RNA splicing. Mice in this line carry about 20 copies of the transgene.
Additional Information
Literature

Transgenic Constructs

This allele contains 1 transgenic construct
Symbol
Expressed Components
Knock-down Targets
None
Regulatory Regions
None
All alleles with this construct

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations