Allele/Variant

Dsg4hage

Species
Mus musculus
Symbol
Dsg4hage
Category
allele
Allele of gene
Dsg4
Transgenic Constructs
None
Synonyms
None
Description
This mutation was induced by the insertion of an early transposon II-ß into intron 8 of the gene locus. The 5,543-bp ETn II-ß was integrated into intron 8, 203 bp away from the initial nucleotide of intron 8; it was flanked by a duplicated 6-bp repeat (ACTAGG) that originated from genomic sequence. 183-bp of this insertion acted as a pseudo exon by being transcribed in-frame, which disrupted the normal coding sequence for the extracellular cadherin repeat 3 (EC3) domain of the gene product.
Additional Information
Literature

Transgenic Constructs

No data available

Genomic Variant Information

No data available

Variant Molecular Consequences

Phenotypes

Disease Associations